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Genetically predicted lower HbA1c via GLP-1R activation showed limited associations with mental well-being and SUDs

Marso, S.P., et al

10.3899/jrheum.160452 139 Shuang LiangD

Target-trial-emulation and cohort analyses report that diabetic patients on GLP-1R agonists develop dementia and Alzheimers disease at lower rates than those on comparator antidiabetic drugs, and pooled analyses of cardiovascular-outcome trials have pointed in the same direction [9]

Additionally, these interactions can span state lines