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"New therapeutic agents are sorely needed if we hope to ease the burden of schistosomiasis on the world's health," said NIH Director Elias A

The Authors This article is Open Access: CC BY 4.0 licence (

This review highlights that for better success, VD deficiency needs to be corrected at multiple levels: (i) VD supplements and/or VD-rich foods need to be consumed to provide adequate VD, and (ii) the body needs to be able to upregulate VD-metabolizing genes to convert VD into 25(OH)VD and then to 1,25(OH)2VD to enhance its metabolic action

The cause of malabsorption needs to be addressed by a health care professional in these cases