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Small molecules such as RSL3 and erastin, which primarily target GPX4 and SLC7A11, respectively, demonstrate that impairment of cystine uptake or lipid peroxide detoxification is sufficient to directly trigger ferroptotic cell death

(Since then, theyve also founded a lobbying group, the Neurotechnology Industry Organization.) Casey and Zack met as undergraduates at U.C.L.A

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These results suggest that basal Gs activation or GLP-1-stimulated Gs activation enhances insulin secretion, relying on protein A kinase and EPAC signals in GLP-1R-MIN-6 cells

Cancer Res 63: 21092117