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A statistically significant increase in thyroid C-cell adenomas was observed in males and females at all dose levels, and a statistically significant increase in thyroid C-cell carcinomas was observed in males at 0.01 mg/kg/day, at clinically relevant exposures

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10.1016/j.metabol.2009.05.014 [DOI] [PubMed] [Google Scholar] 67.Malaguarnera M, Vacante M, Avitabile T, Malaguarnera M, Cammalleri L, Motta M

Interestingly, however, this participants PHQ-9 score increased from 6 to 10: when individual items were examined, mood stayed the same with the change in score secondary to increased fatigue and change in appetite