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Tirzepatide is a single molecule that activates the body's receptors for GIP and GLP-1, which are natural incretin hormones

Acta Neuropsychiatr ., 29 (6), 337346

Although both DSIPs and opioid drugs act on the same receptors in the CNS, as has been found in research in rat models, there is as yet no indication at all that the administration of DSIPs causes a similar addiction

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This condition is characterized by a delay in the movement of stool through the colon, leading to symptoms such as infrequent bowel movements and difficulty passing stools despite adequate effort