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These might include: Persistent fatigue that seems disproportionate to liver disease severity Glossitis (sore, red tongue) or mouth ulcers Shortness of breath and palpitations due to anaemia Difficulty concentrating or 'brain fog' Mood disturbances including irritability or depression It is crucial to recognise that some symptomsparticularly fatigue and cognitive changesare common in both fatty liver disease and B12 deficiency, potentially leading to delayed diagnosis

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Some NHS/ICB guidance notes oral options for dietary-related deficiency, and that long-term injection schedules depend on the cause

HA may exert a chondroprotective effect through anti-inflammatory properties and improved joint lubrication, while AOD9604 may activate developmental pathways that support cartilage regeneration