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Data for this comes from the following two studies

In the treatment of RA, natural products can be used to treat RA through multiple pathways by regulating the activation of Nrf2 through their advantages of targeting multiple proteins and pathways

10.1128/JVI.01519-06 Rocha-Perugini V, Montpellier C, Delgrange D, Wychowski C, Helle F, Pillez A, Drobecq H, Le Naour F, Charrin S, Levy S, et al .: The CD81 partner EWI-2wint inhibits hepatitis C virus entry

in type 2 diabetes, this is blunted or absent, but GLP-1 can revive insulin secretion

The combination of PRMT5 inhibitors with chemotherapeutic drugs can delay the recurrence of SCLC