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Aside from painless administration, MN arrays provide numerous advantages, including the absence of bleeding, controlled drug release, minimal pathogen introduction, reduction in transdermal dosage variability of small compounds, and concerns associated with infections [266, 271, 272]

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Among the most promising therapeutic approaches, much research interest has been devoted to catalytic metal-based anticancer agents that could convert natural biomolecules into (cytotoxic) products or products that ultimately lead to cell death

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Ghusn, W., De la Rosa, A., Sacoto, D., Cifuentes, L., Campos, A., Feris, F., Hurtado, M