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Chronic dosing studies also support a wide margin

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It serves as an obligate co-substrate for multiple enzyme families, including glutathione peroxidases (GPx), glutathione S-transferases (GST), and glutaredoxins, where it contributes to redox-regulated biochemical pathways and enzyme-mediated signaling processes

[Abstract]2026 Apr 8:2026.04.07.716956

However, when this strain was treated with BSO, an inhibitor of GSH synthesis, its ability to counteract the oxidative stress dropped, demonstrating that an active GSH synthesis was the cause of CO23FLC viability in the oxidative environment