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The autoantigens believed to cause the autoreactivity are the alpha and beta subunits of the sodium-potassium pump

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For a patient dealing with early nausea, persistent constipation, or symptoms that return after a treatment change, an individualized review may consider medical history, current medications, symptom severity, hydration, food intake, previous gastrointestinal concerns, and overall treatment goals

Meissner, W., Ravenscroft, P., Reese, R., Harnack, D., Morgenstern, R., Kupsch, A., Klitgaard, H., Bioulac, B., Gross, C