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this mitochondrial localization may allow Nrf2 to directly sense and respond to mitochondrial ROS (71)

Beyond enhancing insulin and glucagon secretion, GLP-1 plays a central role in satiety regulation, appetite suppression, and even maintenance of mood and cognition [31, 32]

Unlike acute wounds, which follow a well-defined healing cascade of re-epithelialization, fibroblast proliferation, and angiogenesis, chronic wounds remain trapped in a prolonged inflammatory phase characterized by microbial persistence and dysregulated immune responses [4,5,6]

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