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In particular, collagen plays a crucial role in maintaining skin health and appearance

In comparison, the prevalence of obesity in adults increased from approximately 28% in 19992000 to 43% in 20172018 [6]

This pharmacokinetic limitation poses a significant challenge for its therapeutic application, as only a small fraction of orally administered AC reaches systemic circulation, reducing its efficacy in vivo

[3] Sublingual and nasal preparations are available but are not routinely recommended within UK clinical guidance and may not be licensed as medicines

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