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Glutathione is a natural antioxidant created by cells

thus, a comprehensive treatment approach must account for these multifaceted dimensions

These diverse observations highlight potential variations in the involvement of SLC38A2 across different pathological subtypes of breast cancer and at various treatment stages, underscoring the need to consider the heterogeneity when targeting SLC38A2 for therapeutic interventions in breast cancer

Developing next-generation selective STAT3 inhibitors targeting unique MDSC-specific pathways or combining upstream regulators (e.g., IL-6, JAK) with myeloid-restricted signals (e.g., S100A8/A9) can enhance specificity

Asmaz, F