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[1] These effects are typically dose-dependent, most pronounced during dose escalation, and tend to diminish over time

Factors like aging, alcohol consumption, and environmental toxins can impact how efficiently B12 is processed, leaving you feeling depleted

With type 2 diabetes Again, semaglutide

So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets

A., Ngomo, S., & Fernandes, K