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it was observed that the onset of ME/CFS was frequently related to an acute respiratory infection or suspected viral infection ( In this case, within the stellate follicle cell population of the adenohypophysis there is a subpopulation of pituitary dendritic cells, which play a role in communicating immune activation to the HPA axis and express HLA-II, and may be a target of EBV infection in some patients ( Patients with ME/CFS may also present autoimmune hypophysitis (60)

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