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Studies, including the UKPDS and DCCT, show that maintaining tight glycemic control soon after diagnosis reduces the risk of long-term complications such as myocardial infarction and all-cause mortality

Failure to document baseline weight can lead to renewal denials

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Preclinical studies further indicate that melatonin enhances neuroprotection by increasing GABA levels, promoting retinal glutamate clearance, and boosting antioxidant activity in animal models of glaucoma (73)