At the starting dose, 12.5 units sits exactly between two syringe markings on a standard insulin syringe
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Osteoclasts are the bone-resorbing cells
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It enhances glucose-dependent insulin secretion, suppresses glucagon release during hyperglycemia, and inhibits hepatic gluconeogenesis, collectively lowering blood glucose and HbA1c without risking hypoglycemia, a critical advantage over traditional antidiabetic agents in HFpEF patients prone to comorbidities [41,42]
