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W., Lee, H., Moon, S., & Chang, I

A panel of healthy males not intending to father children was also included in part II to receive multiple doses of the ActA mAb once toxicology studies in non-human primates revealed an absence of testicular toxicity (see Supplementary Results for complete details of these preclinical studies)

Results: Mounjaro: 20.2% average weight loss Wegovy: 13.7% average weight loss Waist circumference reduction: 18.4cm (Mounjaro) vs 13.0cm (Wegovy) Achieving 20%+ weight loss: 1 in 3 Mounjaro patients vs significantly fewer on Wegovy Thats about 47% more weight loss on average with Mounjaro

Consult your healthcare professional before discontinuing contraception to plan safely

[DOI] [PubMed] [Google Scholar] 85.Otterbein LE, Soares MP, Yamashita K, Bach FH