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Inclusion criteria required participants to be over age 18, read and speak English, have a Hoehn & Yahr score between 2 and 3 (bilateral disease, not severely disabled), and have three or more of the required positive criteria for the diagnosis of definite PD from Step 3 of the UK Brain Bank Diagnostic Criteria for PD

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Morning protocol: Take immediately upon waking Wait 20-30 minutes before eating Pair with a glass of room-temperature water Add vitamin C supplements for enhanced absorption Evening doses work better for people with sensitive stomachs or inconsistent morning routines

The combination has not been studied as a combination