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In patients who develop unexplained lethargy and vomiting or changes in mental status, hyperammonemic encephalopathy should be considered and an ammonia level should be measured

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rigorous human clinical trials are limited

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In a recent roundtable discussion, experts from the Houston Methodist Underwood Center for Digestive Health and MD Anderson Cancer Center discussed new evidence and an emerging consensus that supports a nuanced and individualized approach while avoiding unnecessary disruptions to patient care

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Hackett, G

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