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This chronic activation impairs neuronal homeostasis, worsens synaptic dysfunction, and ultimately accelerates neurodegenerative processes [113116]

The authors thank Claire Bocage for providing project management support for the Carelon Research group during this study

Although new medications, including complement inhibitors and FcRn blockers, have well-documented clinical efficacy, they have not yet been approved for reimbursement in Norway, which is concerning

With so many therapies available, how do clinicians decide what comes next

Constipation may lead to increased straining, which places added pressure on the pelvic floor muscles