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The Framingham [46, 47] and SCORE [48] models were not used because they did not include patients with established CVD, which constituted the majority of subjects in the CVOTs in our analysis, as prior CVD is generally considered to be an important risk factor for new events [49]

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Individuals vary greatly, especially when it comes to weight loss

Here is everything we know about TRIUMPH-1, what we expect from the data, and why this trial matters