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Therefore, the dispensability of SLC7A11 in normal systems and its high expression in various cancers makes it an attractive therapeutic target for cancer treatment

In vivo and in vitro models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expression of genes related to glutathione anabolic metabolism (GCLC, GCLM, and SLC7A11) was significantly down-regulated

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Overuse or unsupervised administration can increase risk,s which is why medical supervision is essential

A well-developed mucus layer is essential for maintaining appropriate host-microbiota interactions and for supporting the optimal function of epithelial tight junctions