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As it has become clear that these drugs are no silver bullet for the disease, Nisenbaum says, the field is really looking at, OK, what comes next? Some companies are working on refining amyloid treatments

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The loss of GSH through the membrane may in turn depend on membrane oxidative stress, because oxidative stress causes lipid peroxidation of cell membrane, leading to altered membrane permeability and transport functions and consequently increased GSH efflux [36]

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