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Flushing or lightheadedness: Reported occasionally in the first few injections

Most researchers notice initial effects like improved recovery and muscle pumps within the first 1-2 weeks

Eur J Clin Pharmacol

Furthermore, because it is not FDA-approved for human use, the supply chain is the Wild West

Nrf2 activation regulates antioxidant responses to modify cellular redox states from predominantly pro-oxidant to antioxidant, and, in an antioxidant environment, macrophage phenotypes shift from M1 pro-inflammatory to M2 anti-inflammatory, reducing the probability of cytokine storms, ARDS, and lethality (Tan et al., 2016