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Injection-site reactions are among the most commonly reported side effects: patients may experience pain, stinging, or mild burning at the IM injection site

4,344 Dipyrimidole (Persantine) works in part by inhibiting platelet phosphodiesterase, an enzyme that increases platelet reactivity

Two downstream consequences are mechanistically central: nicotinamide is preserved for re-entry into the NAD+ salvage pathway (raising intracellular NAD+ availability), and SAM is preserved for other methylation reactions

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A qualified provider should disclose all potential side effects during a pre-injection consultation before administering the shot