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Most of the significant weight loss occurs after you reach your maintenance dose and sustain it for several months

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Contact your GP within 2448 hours for: Persistent pale or grey stools without jaundice Unexplained changes in stool colour lasting more than a few days Greasy, foul-smelling stools that float (steatorrhoea) suggesting fat malabsorption Stool changes accompanied by unexplained weight loss, fever, or night sweats Severe or persistent diarrhoea (more than seven days) or constipation unresponsive to usual measures It is particularly important to report stool changes if you have a history of gallbladder disease, pancreatitis, or inflammatory bowel conditions