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Medical Review Author: Karla K

Regarding between-drug comparisons, both tirzepatide 10 and 15mg were more efficacious in lowering body weight versus semaglutide 0.5, 1.0, and 2.0mg, while tirzepatide 5mg was more efficacious versus semaglutide 0.5 and 1.0mg

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Example 6 Arg34GLP-1 (9-37) carries out the modification of terminal amino group: 1g Boc-His (Trt) -Aib-OH was dissolved in 10mL of dichloromethane, and 0.37g DIC was added