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doi: 10.1007/s42000-020-00173-2 96 NiethammerPGrabherCLookATMitchisonTJ

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On exposure to a toxic dose of APAP, ferrous iron is released into the cytosol from the ruptured lysosomes ( The current results showed that APAP treatment induced a statistically significant increase in MDA and a decrease in GSH levels compared to the control group, while PA produced a significant improvement in oxidative stress by decreasing the MDA level and increasing the GSH level compared to the APAP group

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