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Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR

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In the low-dose treatment group, the researchers reported score improvements, but they were not statistically significant

The cytokines secreted by Th1 and Th17 cells (e.g., IFN- and IL-17) can directly act on hepatic stellate cells, stimulating their activation and proliferation, which leads to the synthesis of extracellular matrix components like collagen and contributes to liver fibrosis [101, 102]

Alex Tatem, a board-certified urologist and member of Rugiet's Medical Advisory Board, will testify at this week's FDA hearings