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It is a conformationally heterogeneous protein that samples multiple active states, encodes ligand identity through a post-translational phosphorylation pattern, and contains at least two structurally separable binding domains that contribute independently to signaling outcome
Nottke A, Colaiacovo MP, Shi Y (2009)
She added that those seeking weight loss purely for aesthetic reasons are usually recommended alternative options such as fat-reduction lasers
Understanding the consequences of NNMT inhibition has implications for research into metabolic regulation and potential therapeutic applications
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