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doi: 10.1146/annurev.micro.112408.134306 42 LewisK

Since sperm DNA disruption can be associated by oxidative and non-oxidative stress (caused by incomplete sperm protamination or aberrant apoptosis), the utilization of DNA fragmentation tests may not be the perfect procedure for identifying individuals with high sperm DNA damage related to oxidative stress

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In summary, the diagnosis of malignant schwannoma involves a multimodal approach combining MRI and PET imaging, tissue biopsy, histopathological assessment, and immunohistochemistry