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These innovations may transform metabolic disease treatment over the next decade

(BMI is an estimate of body fat based on height and weight.) The results indicate a shift in how weight-loss surgery candidates are viewing their treatment options, researchers said

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For example, the potent anti-inflammatory effects (Section 4.1) that shift microglia to a reparative M2 phenotype may be a direct prerequisite for effective remyelination (Section 4.3), as pro-inflammatory M1 microglia are known to inhibit oligodendrocyte progenitor cell (OPC) differentiation