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According to a randomized controlled trial, tapentadol (100250 mg) was effective and well tolerated for the management of moderate-to-severe chronic pain associated with DPN [131]

Antidiabetic medications and the risk of prostate cancer in patients with diabetes mellitus: a systematic review and meta-analysis

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Based on recent studies, SGLT2 inhibitors (SGLTis) are generally considered superior to GLP-1 receptor agonists (GLP-1s) for slowing the progression of chronic kidney disease