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"If you're experiencing diarrhea or constipation, you may need more water than usual to stay hydrated." 2

Additional research has also shown that GLP-1 therapy can increase natural killer (NK) cells

However, the long-term results tell a more nuanced story

Watch for: Significantly decreased urine output Dark-colored urine that does not improve with hydration Swelling in the ankles or feet Persistent fatigue with decreased urination Semaglutide side effects compared to other GLP-1 medications If you are considering semaglutide versus tirzepatide or evaluating other options, understanding how side effect profiles compare helps inform decision-making

In January, FDA regulators gave the OK for another Novo Nordisk product, Wegovy, to be sold as an oral tablet