Paracetamol: overdose-induced oxidative stress toxicity, metabolism, and protective effects of various compounds in vivo and in vitro
When managing patients taking opioid analgesics, particularly those who have been treated for an extended period of time, and/or with high doses for chronic pain, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper
Antioxidant vitamins, C and E, or pomegranate juice, can increase PON1 levels.[ref] For people with the PON1 variant, you may want to consider how many antioxidant-rich foods you eat each day
Ridker PM, Danielson E, Fonseca FAH, Genest J, Gotto AM, Kastelein JJP, et al
phase I metabolic reactions and phase II metabolic reactions