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However, P62 is a substrate for autophagy degradation, and a high level of P62 indicates a low level of autophagy [166]

Each wall of the box possessed two floor-level holes for a total of 8 holes, with seven blocked by an inset cap and one left open connected to an s-curved escape tube to a darkened empty mouse cage

Therefore, in combination with vitamin status and methionine intake, this negative interaction between age and homocysteinemia might be taken into account in future epidemiologic studies, which should use age- and gender-specific reference ranges