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In our experience, glutathione simply does not work optimally without a co-factor to keep it active in the body

Glutathione boosts the utilization and recycling of other antioxidants, namely vitamin C, E, alpha lipoic acid and CoQ10. NAC is able to increase cell protection against oxidative stress which is accomplished through the release of cysteine, which is the rate-limiting precursor in the synthesis of glutathione