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Under normal conditions, APAP is metabolized via conjugation with sulfate and glucuronide, leading to its excretion in the urine

This may involve mtDNA biomarker-guided ART selection, where screening for pre-existing mtDNA haplogroups or mutational burdens identifies individuals at higher risk for specific ART toxicities, enabling proactive selection of less harmful regimen (e.g., avoiding certain NRTIs in susceptible individuals)

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Vitamin C (40 mg): A well-known antioxidant that supports immune function, enhances collagen synthesis, and helps protect the skin from UV damage