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These include: Nausea: Reported in 16% to 20% of patients in clinical trials

Retatrutide has been studied for obesity and type 2 diabetes outcomes, while cagrilintide has been studied for weight management, often alongside GLP1based therapy

(Other commonly cited behaviors include impulsive shopping, drinking, and smoking.) Jessica Duncan, MD, a board-certified obesity medicine physician based in Atlanta, Georgia, says that this could be because "[GLP-1s] also act on the brain's dopamine and reward pathways, which is why patients often notice their cravings drop across the board, not just for food." Dr

However, the core medication responsible for those potent appetite-regulating effects remains unchanged

Hediger MA et al