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The remaining 33% exits through feces
In vitro studies demonstrated that Epitalon induced telomerase and lengthened telomeres in human cell cultures, allowing cells to continue dividing beyond the usual Hayflick limit [9]
An inverse correlation between miR-142 and SIRT1 expression was observed in the brains of long-lived aged rhesus macaques ( In astrocytes, epigenetic regulations in their senescence remains under investigation (Labarta-Bajo and Allen, 2025), while several studies have reported the histone acetylation and increased H3K27ac enrichment in AD astrocytes Li X
Author Contribution IB: collection and analysis of literature, writing original draft
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