The RPKM-processed data available from the authors were retrieved from the Gene Expression Omnibus (GEO) database (GSE49642, GSE52656, GSE62190, GSE66917, and GSE67039)
Published literature describes: In-vitro cellular assays:Peptide concentrations typically range from nanomolar to low micromolar levels, depending on cell type and signaling endpoints measured Receptor binding studies:Concentrations optimized for kinetic and competitive binding analysis Preclinical animal models:Variable dosing based on animal species, route of administration, study duration, and specific biological parameters evaluated How should MT-1 be stored and handled
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Iyob-Tessema H, Wang CS, Kennedy S, Reyes L, Shin S, Greenbaum LA, Hogan J (2021) Grip strength in adults and children with cystinosis