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Although clinical translation is constrained by poor solubility and bioavailability, emerging nanocarrier and prodrug strategies markedly improve luteolins pharmacokinetic profile

however, additional work is required to establish this mechanism

10.31083/FBL27954 98

Research potential persists: Despite clinical failure, AOD-9604 remains useful as a laboratory model for studying growth-hormone fragment signaling, adipocyte biochemistry, and peptide-receptor interactions

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