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Epub 2014 Aug 13

The exceptional in vitro potency is attributed to its mechanism of acting as an allosteric potentiator of HGF binding to c-Met (amplifying an endogenous signal), which produces non-linear dose-response curves

Severe or continuing vomiting and diarrhea may lead to dehydration and possible kidney problems

These conditions are associated with an increased risk of thyroid carcinoma and MEN 2 syndrome when using GLP-1 medications

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