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Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, et al
GLP-1 and GIP stimulate insulin secretion from these cells in a glucose-dependent manner, meaning that insulin release intensifies in response to heightened plasma glucose levels
Sertraline requires daily dosing for optimal effect and should not be stopped abruptly due to the risk of discontinuation syndrome
Further prospective studies are needed to control for potential confounders and better assess the true impact of GLP-1 RA use on EGD outcomes
In summary, understanding the immunomodulation occurring during SARS-CoV-2 infection is crucial for identifying therapeutic targets and developing effective medications as well as understanding its pathogenesis
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