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Metabolic Control Forty-two diabetic subjects for whom complete serial A 1c determinations were available (n = 42) had good baseline glycemic control as evidenced by mean Hb A 1c values of 7.3% (55.8 mmol/mol) in the ARA 290 group (n = 21) and 6.9% (52.1 mmol/mol) in the placebo group (n = 21)

( G ) Time course of plasma glucose and glucose infusion rates, and endpoint GIR during hyperinsulinemic-euglycemic clamp of Dpp4 GFP ( n = 4) and Dpp4 hep/ ( n = 5) mice

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