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Overall Evidence for the Use of B12 for Painful Peripheral Polyneuropathy Taking into account the above evidence, there is level III evidence overall to support the use of B12 either as monotherapy or as a combination therapy for treating neuropathic pain caused by peripheral polyneuropathy

Additionally, in order for your body to absorb vitamin B12 from the food you eat, you need an adequate amount of stomach acid and a special protein called intrinsic factor

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