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The FDA's pharmacovigilance reports include cases of acute kidney injury (AKI) occurring in the context of semaglutide-associated GI side effects, some progressing to hospitalization [8]

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The activity of NRF2 is primarily regulated post-translationally through its interaction with Kelch-like ECH-associated protein 1 (KEAP1), a crucial regulator of NRF2 under basal redox conditions

For instance, IL-1 disrupts LTP by modulating NMDA receptor activity (Lynch, 2015

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