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J Bacteriol 188(2):609618 Kruman II, Culmsee C, Chan SL, Kruman Y, Guo Z, Penix L, Mattson MP (2000) Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

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When you hurt your ankle, it usually swells

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Drinking adequate water also keeps the skin hydrated, which improves brightness and texture over time