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During an attack , the mechanisms responsible for pain transmission are activated excessively, which leads to the release of molecules capable of amplifying the painful sensation and promoting inflammation

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Encourage a low-sodium and low-protein diet

The final figures below are from the peer-reviewed publication in The Lancet (June 6, 2026): Weight loss was lower than in the obesity population, consistent with the established pattern that individuals with type 2 diabetes lose less weight than those without diabetes on the same agents